The present invention relates to carbohydrates capable of acting as receptors for malaria antigens present on the surfaces of malaria infected erythrocytes. The receptors according to the invention comprises negatively charged glycosaminoglycan-like moities, preferably sulphated. The invention also relates to novel malaria polypeptides capable of acting as ligands in relation to the receptors according to the invention. The invention also encompasses the use thereof as medicaments, pharmaceutical compositions containing the same as well as antibodies directed against said new ligands.
申请公布号
ES2257818(T3)
申请公布日期
2006.08.01
申请号
ES19980945703T
申请日期
1998.09.18
申请人
WAHLGREN, MATS;QIJUN, CHEN
发明人
WAHLGREN, MATS;BARRAGAN, ANTONIO;CARLSON, JOHAN, MICROB. & TUMOR BIO. CENTER (MTC);QIJUN, CHEN, MICROB. & TUMOR BIO. CENTER (MTC);FERNANDEZ, VICTOR, MICROB. & TUMOR BIO. CENTER (MTC)