MODULATORS OF RETINOL-RETINOL BINDING PROTEIN (RBP)-TRANSTHYRETIN (TTR) COMPLEX FORMATION
摘要
Described herein are methods and compositions for the detection of transthyretin (TTR), retinol binding protein (RBP) and retinol complex formation. The methods and compositions described herein also provide for the screening of modulators of retinol-RBP-TTR complex formation. Furthermore, the methods and compositions provide for therapeutic agents for the treatment and/or prevention of age-related macular degeneration and/or dystrophies.
申请公布号
WO2006052860(A3)
申请公布日期
2006.07.27
申请号
WO2005US40236
申请日期
2005.11.04
申请人
SYTERA, INC.;MATA, NATHAN, L.;HAN, YUN;WIDDER, KENNETH;LICHTER, JAY
发明人
MATA, NATHAN, L.;HAN, YUN;WIDDER, KENNETH;LICHTER, JAY