发明名称 |
TISSUE FACTOR PHOSPHOLIPID VESICLE PARTICLES AND METHODS OF USE FOR COAGULATION |
摘要 |
Tissue Factor (natural or recombinant truncated) can be incorporated into stable, soluble nanoscale particles so that activity is maintained. These particles can be used as a reagent in prothrombin clotting time assays or they can be used in therapeutic compositions for use in humans or animals. Therapeutic settings can include supplementation in the case of a genetic deficiency, uncontrolled bleeding, surgical incisions or seepage, thrombocytopenia, soft tissue trauma or other trauma, to effect tumor regression or to inhibit tumor growth.
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申请公布号 |
WO2006047684(A3) |
申请公布日期 |
2006.07.27 |
申请号 |
WO2005US38781 |
申请日期 |
2005.10.27 |
申请人 |
THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, ET AL.;MORRISSEY, JAMES H.;PUREZA, VINCENT S.;SLIGAR, STEPHEN G. |
发明人 |
MORRISSEY, JAMES H.;PUREZA, VINCENT S.;SLIGAR, STEPHEN G. |
分类号 |
A61K38/00;C07K14/00 |
主分类号 |
A61K38/00 |
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