摘要 |
PROBLEM TO BE SOLVED: To provide a method for producing 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid represented by chemical formula 1 from 2,3-bis(benzylamino)succinic acid and phosgene in good operability in good yield. SOLUTION: The 1,3-dibenzyl-2-oxoimidazolidine-4,5-dicarboxylic acid is produced by reacting the 2,3-bis(benzylamino)succinic acid with the phosgene in a two-phase type solvent comprising a monochlorobenzene and water. COPYRIGHT: (C)2006,JPO&NCIPI
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