发明名称 |
2-Alkoxyphenyl substituted imidazotriazinones |
摘要 |
The 2-phenyl-substituted imidazotriazinones having short unbranched alkyl radicals in the 9-position are prepared from the corresponding 2-phenyl-imidazotriazinones by chlorosulphonation and subsequent reaction with the amines. The compounds inhibit cGMP-metabolising phosphodiesterases and are suitable for use as active compounds in pharmaceuticals, for treating cardiovascular and cerebrovascular disorders and/or disorders of the urogenital system, in particular for treating erectile dysfunction.
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申请公布号 |
US2006160810(A1) |
申请公布日期 |
2006.07.20 |
申请号 |
US20030467966 |
申请日期 |
2003.12.12 |
申请人 |
NIEWOHNER ULRICH;NIEWOHNER MARIA T;HANING HELMUT;RADTKE MARTIN;SEIDEL DIETRICH;BISCHOFF ERWIN;KARL WOLFGANG |
发明人 |
NIEWOHNER ULRICH;NIEWOHNER MARIA T.;HANING HELMUT;RADTKE MARTIN;SEIDEL DIETRICH;BISCHOFF ERWIN;KARL WOLFGANG |
分类号 |
A61K31/53;A61P9/08;A61P9/10;A61P13/00;A61P15/10;C07D487/04 |
主分类号 |
A61K31/53 |
代理机构 |
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主权项 |
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地址 |
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