| 发明名称 |
IMIDE AS TNFalpha INHIBITOR |
| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for lowering the TNFαlevel of mammals, and a compound and a composition useful for the method. <P>SOLUTION: Imides act as inhibitors of tumor necrosis factorαand can be used to combat cachexia, endotoxic shock, and retrovirus replication. <P>COPYRIGHT: (C)2006,JPO&NCIPI</p> |
| 申请公布号 |
JP2006188530(A) |
申请公布日期 |
2006.07.20 |
| 申请号 |
JP20060039637 |
申请日期 |
2006.02.16 |
| 申请人 |
CELGENE CORP;MULLER GEORGE W |
发明人 |
MULLER GEORGE W |
| 分类号 |
C07C275/42;C07D307/66;A61K31/16;A61K31/165;A61K31/215;A61K31/275;A61K31/33;A61K31/34;A61K31/341;A61K31/40;A61K31/4015;A61K31/403;A61K31/4035;A61K31/404;A61K31/405;A61K31/415;A61K31/4178;A61K31/4188;A61K31/435;A61K31/437;A61K31/44;A61K31/4406;A61K31/4427;A61K31/443;A61K31/4465;A61K31/45;A61K31/454;A61K31/4545;A61P1/04;A61P9/04;A61P9/10;A61P11/00;A61P17/00;A61P17/02;A61P17/06;A61P19/02;A61P21/00;A61P25/00;A61P29/00;A61P31/04;A61P31/12;A61P31/14;A61P31/16;A61P31/18;A61P31/20;A61P31/22;A61P33/06;A61P35/00;A61P37/00;A61P37/04;A61P37/06;A61P43/00;C07C211/27;C07C229/08;C07C229/20;C07C229/22;C07C229/34;C07C233/11;C07C237/04;C07C255/50;C07D209/08;C07D209/18;C07D209/46;C07D209/48;C07D209/66;C07D209/76;C07D211/88;C07D213/55;C07D213/75;C07D401/04;C07D401/06;C07D401/12;C07D403/06;C07D405/12;C07D471/04;C07D487/04;C07D495/04 |
主分类号 |
C07C275/42 |
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