PROCESS FOR PREPARATION OF 3-PIPERAZINYLBENZISOTHIAZOLES

摘要

The present invention is directed to a process for preparing 3-piperazinylbenzisothiazoles. The process comprises reacting a specified 3-halo-1,2-benzisothiazole or 2-cyanobenzenesulfenyl halide in the presence of an alkylene glycol derivative. The process is industrially effective, easy and economical and can provide useful intermediates for the production of pharmaceutical preparations.