СПОСОБ ОПРЕДЕЛЕНИЯ ХАРАКТЕРА КОЖНОЙ ТУБЕРКУЛИНОВОЙ ГИПЕРЧУВСТВИТЕЛЬНОСТИ IN VITRO

摘要

FIELD: clinical diagnosis, in particular in vitro determination of skin tuberculin high-grade sensitivity. ^ SUBSTANCE: skin tuberculin high-grade sensitivity is determined based on alteration of fluorescent intensity of common leucocytal CD45 antigen and isoforms thereof CD45RA and CD45RO in test probe (after incubation of peripheral blood with 2TE tuberculin solution) in contrast to control probe with physiological solution by using monoclonal antibodies labeled with fluorescein isothiocyanate (FITC) and laser flow cytofluorometry. ^ EFFECT: new method for in vitro determination of skin tuberculin high-grade sensitivity. ^ 1 tbl, 4 ex