| 摘要 |
The present invention provides a biochip substrate used for immobilizing biomaterials, which has a matrix and at least one metal oxide thread-like nano-object formed vertically on a surface of the matrix. The metal oxide thread-like nano-object is employed for immobilizing the biomaterial onto the matrix of the chip substrate directly, without complicated immobilizing processes by using cross-linking agents or curing agents, and thereby simplifying the process of fabrication. Arrangement as such makes it suitable for purification of a biomaterial. On the other hand, the metal oxide thread-like nano-object characterized by having an enormous surface area is suitable for fabricating immunosensor chip and capable of maintaining high activity and reactivity of biomaterials, so as to increase speed and yield of reactions.
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