发明名称 |
Methods for blocking binding of CD28 receptor to B7 |
摘要 |
The invention identifies the B7 antigen as a ligand that is reactive with the CD28 receptor on T cells. The invention further provides methods for using antibodies to B7, or fragments thereof, to regulate CD28 positive T cell response and immune responses mediated by T cells.
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申请公布号 |
US7070776(B1) |
申请公布日期 |
2006.07.04 |
申请号 |
US19950459766 |
申请日期 |
1995.06.02 |
申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
LINSLEY PETER S.;LEDBETTER JEFFREY A.;DAMLE NITIN K.;BRADY WILLIAM |
分类号 |
A61K39/395;A61K38/00;C07K14/705;C07K16/28;G01N33/569 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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