发明名称 |
Ligand-controlled regulation of endogenous gene expression |
摘要 |
Disclosed herein are compositions comprising an engineered zinc finger protein and a nuclear hormone receptor transcriptional control domain, polynucleotides encoding one or more components of the compositions, methods of making the compositions and methods of using these compositions, for example to modulate gene expression and/or to generate transgenic plants or animals.
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申请公布号 |
US7070934(B2) |
申请公布日期 |
2006.07.04 |
申请号 |
US20030456444 |
申请日期 |
2003.06.05 |
申请人 |
SANGAMO BIOSCIENCES, INC. |
发明人 |
COX, III GEORGE NORBERT;CASE CASEY CHRISTOPHER;EISENBERG STEPHEN P.;JARVIS ERIC EDWARD;SPRATT SHARON KAYE |
分类号 |
C12Q1/68;C12N15/00;C12N15/09;C12N15/63;C12N15/70 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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