发明名称 NUCLEIC ACID FRAGMENT FOR DETECTING NUCLEIC ACID AND METHOD OF DETECTING NUCLEIC ACID
摘要 <P>PROBLEM TO BE SOLVED: To provide a fragment of nucleic acid for detecting mutation or polymorph of the subjective nucleic acid in a nucleic acid sample, excellent in detecting accuracy and to provide a method for the same. <P>SOLUTION: The invention relates to a set of nucleic acid fragments comprising a plurality of nucleic acid fragments hybridizable to each of a plurality of target sequences, wherein each nucleic acid fragment has mutually connectable domains and the affinity of the mutually connectable domains are set higher than the affinity of the target sequence with other nucleic acid fragments. The fragment are used in the set of the nucleic acid fragments. The fragments of the nucleic acid are used as a probe for detecting a nucleic acid or a competitor for nucleic acid detection. The fragment is usable for detecting e.g. human leukocyte antigen(HLA) gene, T-cell receptor gene, erythrocyte-type determining gene and Rh antigen gene with high precision. <P>COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006166911(A) 申请公布日期 2006.06.29
申请号 JP20050335631 申请日期 2005.11.21
申请人 WAKUNAGA PHARMACEUT CO LTD 发明人 NAOHARA HIROSHI;KAWAI SHINTARO;OKA TAKANORI
分类号 C12N15/09;C12Q1/68;G01N33/53 主分类号 C12N15/09
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