发明名称 |
AGENT FOR RECONSTRUCTING NEURAL NETWORK COMPRISING CHINESE MEDICINE FORMULATION AND METHOD OF RECONSTRUCTING NEURAL NETWORK |
摘要 |
<p>[PROBLEMS] Neurodegenerative diseases such as Alzheimer's disease, senile dementia, cerebrovascular dementia and Parkinson's disease indicate symptoms with disorders in memory and cognition due to impairments in the neural network, though causal factors thereof vary from disease to disease. Since there is no efficacious means of treating these diseases, it has been required to establish a therapy whereby nerve functions can be brought toward normality even in the case where impairments in the neural network have already proceeded. Thus, it is intended to develop a Chinese medicine formulation usable in such a therapy. [MEANS FOR SOLVING PROBLEMS] Cultured nerve cells are made into a state showing contraction of axons and dendrites and decreases in the presynaptic and postsynaptic elements. Then attempts are made to search for a Chinese medicine formulation by which the nerve cells in the above-described state can be treated so that the neurites and synapses of the nerve cells can be normalized. As a result, it is found out that a Chinese medicine formulation comprising an extract of notoginseng radix and/or ginseng radix, astragalus root, calamus and hoelen is useful as an agent for reconstructing the neural network.</p> |
申请公布号 |
WO2006068155(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
WO2005JP23412 |
申请日期 |
2005.12.20 |
申请人 |
NATIONAL UNIVERSITY CORPORATION UNIVERSITY OF TOYAMA;TOHDA, CHIHIRO;KOMATSU, KATSUKO |
发明人 |
TOHDA, CHIHIRO;KOMATSU, KATSUKO |
分类号 |
A61K36/888;A61K36/258;A61K36/076;A61K36/48;A61P21/04;A61P25/14;A61P25/16;A61P25/28;A61P35/00 |
主分类号 |
A61K36/888 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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