发明名称 |
Modulation of oligonucleotide CpG-mediated immune stimulation by positional modification of nucleosides |
摘要 |
The invention provides methods for modulating the immune response caused by CpG dinucleotide-containing compounds. The methods according to the invention enables both decreasing the immunostimulatory effect for antisense applications, as well as increasing the immunostimulatory effect for immunotherapy applications.
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申请公布号 |
US2006142556(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
US20050274043 |
申请日期 |
2005.11.15 |
申请人 |
IDERA PHARMACEUTICALS, INC. |
发明人 |
AGRAWAL SUDHIR |
分类号 |
C07H21/02;C12N15/09;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K48/00;A61P37/02;A61P37/04;A61P37/06;C07H21/00;C07H21/04;C12N15/113;C12N15/117 |
主分类号 |
C07H21/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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