发明名称 |
SUBSTRATE RECOGNITION BY DIFFERENTIABLE HUMAN MESENCHYMAL STEM CELLS |
摘要 |
<p>The invention described herein provides a structure for growing isolated differentiable human mesenchymal cells, which includes a three-dimensional matrix of fibers. The matrix serves as an implantable scaffolding for delivery of differentiable human mesenchymal cells in tissue engineering. The invention further provides compositions that contain the three-dimensional matrix of fibers seeded with isolated differentiable human mesenchymal cells, wherein the matrix forms a supporting scaffold for growing the isolated differentiable human mesenchymal cells, and wherein the differentiable human mesenchymal cells differentiate into a mature cell phenotype. The invention further provides methods of preparing the implantable nanofiber matrix scaffolding seeded with differentiable human mesenchymal cells for use in tissue engineering.</p> |
申请公布号 |
CA2596957(A1) |
申请公布日期 |
2006.06.29 |
申请号 |
CA20052596957 |
申请日期 |
2005.12.01 |
申请人 |
NEW JERSEY INSTITUTE OF TECHNOLOGY |
发明人 |
SHANMUGASUNDARAM, SHOBANA;JAFFE, MICHAEL;ARINZEH, TREENA |
分类号 |
H03L7/00;C12N5/077;C12N5/0775 |
主分类号 |
H03L7/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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