发明名称 Proline derivatives and use thereof as drugs
摘要 The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products. The present inventors have found that derivatives having a substituent introduced into the gamma-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.
申请公布号 US7060722(B2) 申请公布日期 2006.06.13
申请号 US20050142523 申请日期 2005.06.02
申请人 发明人
分类号 A61K31/4025;A61K31/427;A61P1/02;A61P3/04;A61P3/10;A61P13/08;A61P17/00;A61P31/18;A61P35/04;A61P37/06;A61P43/00;C07D207/16;C07D401/14;C07D403/14;C07D413/14;C07D417/06;C07D417/14;C07D471/10;C07D487/04;C07D498/04 主分类号 A61K31/4025
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