发明名称 |
BIOINTERFACE WITH MACRO- AND MICRO- ARCHITECTURE |
摘要 |
Disclosed herein are biointerface membranes including a macro-architecture and a micro-architecture co-continuous with and bonded to and/or located within at least a portion of the macro-architecture.The macro- and micro-architectures work together to manage and manipulate the high-level tissue organization and the low-level cellular organization of the foreign body response in vivo, thereby increasing neovascularization close to a device-tissue interface, interfering with barrier cell layer formation, and providing good tissue anchoring, while reducing the effects of motion artifact, and disrupting the organization and/or contracture of the foreign body capsule. The biointerface membranes of the preferred embodiments can be utilized with implantable devices such as devices for the detection of analyte concentrations in a biological sample (for example, from a body), cell transplantation devices, drug delivery devices, electrical signal delivering or measuring devices, and/or combinations thereof. |
申请公布号 |
WO2005079257(A3) |
申请公布日期 |
2006.06.08 |
申请号 |
WO2005US04058 |
申请日期 |
2005.02.09 |
申请人 |
DEXCOM, INC.;CARR-BRENDEL, VICTORIA;SIMPSON, PETER, C.;BRAUKER, JAMES, H. |
发明人 |
CARR-BRENDEL, VICTORIA;SIMPSON, PETER, C.;BRAUKER, JAMES, H. |
分类号 |
A61F2/00;A61F13/00;A61L31/10;A61L31/14;A61L31/16 |
主分类号 |
A61F2/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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