| 摘要 |
<P>PROBLEM TO BE SOLVED: To significantly enhance sensitivity of a nucleic acid detecting sensor using an FET (field-effect transistor). <P>SOLUTION: In the nucleic acid detecting sensor for detecting a target nucleus acid molecule 109 with a special alignment included in specimen on the basis of the intensity of characteristics modulation of FET, by fixing at least a probe nucleus acid molecule 102 hybridizable with the target nucleus acid molecule to a gate 101 of the aforementioned FET, a gate width of the FET is obtained in the order of (ε<SB>0</SB>ε<SB>r</SB>k<SB>B</SB>T/e<SP>2</SP>n)<SP>1/2</SP>, where ε<SB>0</SB>is the dielectric constant of vacuum, ε<SB>r</SB>the relative permittivity of channel domain, k<SB>B</SB>the Boltzmann constant, T the absolute temperature of the channel domain of FET, e the elementary charge, and n the carrier density. <P>COPYRIGHT: (C)2006,JPO&NCIPI |
