发明名称 |
COMPOSITIONS AND METHODS FOR RESTORING SENSITIVITY TO TREATMENT WITH HER2 ANTAGONISTS |
摘要 |
<p>Methods and compositions for restoring growth inhibition sensitivity to a tumor cell resistant to growth inhibition by HER2 antagonists. The methods involve administering a PCDGF antagonist to the cell in an amount effective to stimulate or restore growth inhibition sensitivity to HER2 antagonists. The invention also provides treatment regimens, and therapeutic compositions comprising an HER2 antagonist and a PCDGF antagonist.</p> |
申请公布号 |
EP1660010(A2) |
申请公布日期 |
2006.05.31 |
申请号 |
EP20040779605 |
申请日期 |
2004.07.30 |
申请人 |
A & G PHARMACEUTICAL, INC. |
发明人 |
SERRERO, GINETTE |
分类号 |
A61K39/395;A61K;A61P35/00;C07K16/22;C07K16/32;G01N33/574;(IPC1-7):A61K6/00 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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