发明名称 Methods of treating gastrointestinal and genitorinary pain disorders using vanilafaxin and derivatives
摘要 This invention provides a method of treating functional gastrointestinal and genitourinary disorders in a mammal by administering to the mammal an effective amount of a hydroxycycloalkane phenethylamine of the following structural formula: in which A is a moiety of the formula where the dotted line represents optional unsaturation; R1 is hydrogen or alkyl; R2 is alkyl; R4 is hydrogen, alkyl, formyl, or alkanol; R5 and R6 are, independently, hydrogen, hydroxyl, alkyl, alkoxy, alkanoyloxy, cyano, nitro, alkylmercapto, amino, alkylamino, dialkylamino, alkanamido, halo, trifluoromethyl, or taken together, methylene dioxy; R7 is hydrogen or alkyl; and n is 0, 1, 2, 3, or 4; or a pharmaceutically acceptable salt thereof.
申请公布号 ZA200410157(B) 申请公布日期 2006.05.31
申请号 ZA20040010157 申请日期 2004.12.15
申请人 WYETH 发明人 KARLSTADT, ROBYN, G.;BURTON, MICHAEL, S.;LYNN, RICHARD, B.;MERVYN DANILEWITZ
分类号 A61K;A61K31/135;A61K31/137;A61K31/277;A61K31/36;A61P;A61P1/00;A61P1/04;A61P13/00 主分类号 A61K
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