发明名称 |
Compositions and methods for treating atherosclerosis |
摘要 |
Peptides and mimetics of selected domains of mammalian serum amyloid A isoform 2.1 (SAA2.1) and compounds and compositions thereof are provided that enhance the effect on macrophage cholesterol ester hydrolase activity and/or inhibit acyl CoA:cholesterol acyl transferase activity. Methods of using these compositions in the treatment and/or prevention of atherosclerosis as well as coronary heart disease and cardiovascular disease are also provided.
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申请公布号 |
US2006111299(A1) |
申请公布日期 |
2006.05.25 |
申请号 |
US20050268690 |
申请日期 |
2005.11.07 |
申请人 |
KISILEVSKY ROBERT;TAM SHUI-PANG;ANCSIN JOHN B;JIA ZONGCHAO |
发明人 |
KISILEVSKY ROBERT;TAM SHUI-PANG;ANCSIN JOHN B.;JIA ZONGCHAO |
分类号 |
A61K38/10;A61K38/00;C07K7/08;C07K14/775 |
主分类号 |
A61K38/10 |
代理机构 |
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地址 |
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