摘要 |
<P>PROBLEM TO BE SOLVED: To perform highly accurate measurement by improving the property of sealing between a hole and cells, to lower the cost of a chip, and to supply cells and chemicals with satisfactory operability, with respect to an electrophysiological measuring instrument. <P>SOLUTION: A member 102 of PDMS, for example, is used wherein the diameter of a patch hole 101 becomes smaller than an original diameter when thereon exerting negative pressure 202. Further, a micro flow-path chip 601 is formed in which a buffer liquid acts as a sheath flow 702 of chemicals, by supplying cells 104 onto the patch hole 101, and placing a buffer liquid supply flow path 602 and a chemical supply flow path 603 in the middle of a flow path of the patch hole 101. <P>COPYRIGHT: (C)2006,JPO&NCIPI |