发明名称 |
COMPOSITION AND METHOD FOR THE TREATMENT OF CANCER AND OTHER PHYSIOLOGIC CONDITIONS BASED ON MODULATION OF THE PPAR-GAMMA PATHWAY AND HER-KINASE AXIS |
摘要 |
<p>Described herein are methods of using a NSAID and a HER-kinase axis inhibitor in the treatment of various conditions including cancer, and especially prostate, breast, lung, ovarian, brain and colon cancers, through regulation of PPARgamma activity. In various embodiments, the NSAID and HER-kinase axis inhibitor may be included in a composition that is useful for the treatment of conditions in a mammal. Also described is a kit including a NSAID and a HER-kinase axis inhibitor along with instructions for their use in treating and preventing disease conditions, such as cancer.</p> |
申请公布号 |
EP1658075(A2) |
申请公布日期 |
2006.05.24 |
申请号 |
EP20040782532 |
申请日期 |
2004.08.27 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
AGUS, DAVID, B.;JAIN, ANJALI;HEDVAT, MICHAEL |
分类号 |
A61K31/47;A61K;A61K31/19;A61K31/407;A61K39/395;A61K45/06;A61P35/00;(IPC1-7):A61K31/47 |
主分类号 |
A61K31/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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