| 发明名称 |
PRMTs as modifiers of the p53 pathway and methods of use |
| 摘要 |
Human PRMT genes are identified as modulators of the p53 pathway, and thus are therapeutic targets for disorders associated with defective p53 function. Methods for identifying modulators of p53, comprising screening for agents that modulate the activity of PRMT are provided.
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| 申请公布号 |
US7049088(B2) |
申请公布日期 |
2006.05.23 |
| 申请号 |
US20020164278 |
申请日期 |
2002.06.05 |
| 申请人 |
EXELIXIS, INC |
发明人 |
FRIEDMAN LORI;PLOWMAN GREGORY D.;BELVIN MARCIA;FRANCIS-LANG HELEN;LI DANXI;FUNKE ROEL P.;RYSECK ROLF PETER;JAYARAMAN LATA;BOL DAVID K.;LORENZI MATTHEW |
| 分类号 |
C12Q1/48;C12N9/10;C12Q1/68;G01N33/574 |
主分类号 |
C12Q1/48 |
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