发明名称 |
Non-invasive gene targeting to ocular cells |
摘要 |
Liposomes containing therapeutic genes are conjugated to multiple targeting agents to provide transport of the encapsulated gene across the blood-retinal barrier and the plasma membrane of ocular cells. Once across the blood-retinal barrier and ocular cell membrane, the encapsulated gene expresses the encoded therapeutic agent within the ocular cells to provide diagnosis and/or treatment of disease.
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申请公布号 |
US2006105982(A1) |
申请公布日期 |
2006.05.18 |
申请号 |
US20050321009 |
申请日期 |
2005.12.28 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA |
发明人 |
PARDRIDGE WILLIAM M. |
分类号 |
A61K48/00;A61K9/127;A61K9/51;A61K31/7088;A61K38/00;A61K38/16;A61K38/28;A61K39/395;A61K47/48;A61P5/48;A61P25/16;A61P35/00;C12N15/88 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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