发明名称 |
Method of preselection patients for anti-VEGF, anti-HIF-1 or anti-thioredoxin therapy |
摘要 |
The present invention generally relates to methods of preselecting patients for treatment with an anti-VEGF therapy, anti-HIF-1 therapy or anti-thioredoxin therapy. Aspects of the invention combine methods of dynamic contrast enhanced-MRI and diffusion weighted-MRI for the detection of tumor histology. The methodology disclosed herein detects tissue blood volume, tumor vascularity, and abnormal capillary permeability, thereby determining tumor vascularity to determine whether a patient should be administered such therapy.
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申请公布号 |
US2006104902(A1) |
申请公布日期 |
2006.05.18 |
申请号 |
US20050206526 |
申请日期 |
2005.08.17 |
申请人 |
POWIS GARTH;KIRKPATRICK LYNN;GILLIES ROBERT J;JORDAN BENEDICTE |
发明人 |
POWIS GARTH;KIRKPATRICK LYNN;GILLIES ROBERT J.;JORDAN BENEDICTE |
分类号 |
A61K49/00;A61K31/4166;A61K39/395 |
主分类号 |
A61K49/00 |
代理机构 |
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主权项 |
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地址 |
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