摘要 |
The present invention provides novel chymopapain isoenzymes, compositions thereof, and methods for locally administering recombinant chymopapain or synthetic chymopapain to treat a disc disorder. Recombinant chymopapain or synthetic chymopapain useful in the methods of the invention can be naturally occurring chymopapain or variant chymopapain, including the novel chymopapain isoenzmyes of the invention. |