摘要 |
<p>A wound treatment agent (A1) comprises a zeolite-iodine inclusion compound (c1). An independent claim is included for a wound-stilling material, where (A1) is covered on the side facing towards the wound, by a porous textile fibrous material (preferably non-woven or knitted fabric) and a moisture-permeable sheet. ACTIVITY : Vulnerary. Physiological saline (45 ml) was admixed with a germ suspension of Staphylococcus aureus to obtain a concentration of 1.5x10 7> cfu/ml. To this germ suspension, zeolite-iodine complex (10%) (1 g) was added, followed by slight agitation. After different periods of time, 1 ml each was removed, and the number of surviving germs was determined by a plate-casting method in TSA-agar. Incubation was effected at 37[deg]C for 24 hours. The results were: sampling after 1 minutes: strong growth; sampling after 5 minutes: no growth; sampling after 15 minutes: no growth; and sampling after 30 minutes: no growth. Thus, the zeolite-iodine complex released so much iodine under these conditions that all the germs were killed. MECHANISM OF ACTION : None given.</p> |