摘要 |
This invention relates generally to compounds and processes for synthesizing derivatives of 2-3-<U STYLE="SINGLE">O-isopropylidene-alpha-L-xylo-2-hexulofuranosonic acid. The compounds of this invention are useful, inter-alia, for the inhibition and prevention of cell adhesion and cell adhesion-mediated pathologies, including inflammatory and autoimmune diseases, such as bronchial asthma rheumatoid arthritis, type I diabetes, multiple sclerosis, allograft rejection and psoriasis. This invention also relates to pharmacological compositions containing derivatives of 2-3-<U STYLE="SINGLE">O-isopropylidene-alpha-L-xylo-2-hexulofuranosonic acid and the methods of treating such pathologies as listed above.
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