Methods and compositions for producing a labeled population of nucleic acids for use in an array-based comparative genome hybridization (CGH) assay are provided. In general, the methods involve cleaving a genomic source to produce a sample containing nucleic acid fragments, and end-labeling the nucleic acid fragments to provide a population of nucleic acids having a terminal label. Kits and systems for use in practising the subject methods are also provided.
申请公布号
EP1647602(A1)
申请公布日期
2006.04.19
申请号
EP20050256313
申请日期
2005.10.11
申请人
AGILENT TECHNOLOGIES, INC.
发明人
CURRY, BO U.;ANDERSON, PAIGE L.;SCHEFFER, ALICIA F.;ILSLEY, DIANE D.;BARRETT MICHAEL T.