The present invention relates to methods that employ peptides or peptide derivatives to inhibit hepatitis C virus infection. The present invention is based in part on the discovery that E2 envelope glycoprotein of hepatitis C virus has previously undescribed domains that are important for interactions with cellular or viral proteins that are necessary for early steps in HCV infection. . The present invention provides peptides and methods of treatment and prophylaxis of diseases induced by hepatitis C virus and related viruses.
申请公布号
WO2006039326(A2)
申请公布日期
2006.04.13
申请号
WO2005US34777
申请日期
2005.09.26
申请人
THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND;THE ROCKEFELLER UNIVERSITY;GARRY, ROBERT, F.;MCKEATING, JANE, A.