发明名称 Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
摘要 The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an enzyme inhibitor, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an enzyme inhibitor in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an enzyme inhibitor. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an enzyme inhibitor and subsequently treated with a dose of an HSP90 inhibitor.
申请公布号 WO2005000213(A3) 申请公布日期 2006.04.13
申请号 WO2004US16889 申请日期 2004.05.28
申请人 JOHNSON, ROBERT, JR.;ZHOU, YIQING;MUELLER, THOMAS;KOSAN BIOSCIENCES, INC. 发明人 JOHNSON, ROBERT, JR.;ZHOU, YIQING;MUELLER, THOMAS
分类号 A61K;A61K31/19;A61K31/33 主分类号 A61K
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