Method for treating diseases using HSP90-inhibiting agents in combination with enzyme inhibitors
摘要
The present invention provides a method for treating cancer. The method involves the administration of an HSP90 inhibitor and an enzyme inhibitor, where the combined administration provides a synergistic effect. In one aspect of the invention, a method of treating cancer is provided where a subject is treated with a dose of an HSP90 inhibitor in one step and a dose of an enzyme inhibitor in another step. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an HSP90 inhibitor and subsequently treated with a dose of an enzyme inhibitor. In another aspect of the invention, a method of treating cancer is provided where a subject is first treated with a dose of an enzyme inhibitor and subsequently treated with a dose of an HSP90 inhibitor.
申请公布号
WO2005000213(A3)
申请公布日期
2006.04.13
申请号
WO2004US16889
申请日期
2004.05.28
申请人
JOHNSON, ROBERT, JR.;ZHOU, YIQING;MUELLER, THOMAS;KOSAN BIOSCIENCES, INC.