APOPTOSIS-INDUCING AGENT INHIBITING GLYOXSALASE I ACTIVITY

摘要

PROBLEM TO BE SOLVED: To provide a glyoxalase I activity-inhibiting agent and an apoptosis-inducing agent, having a new skeleton without having GSH (glutathione) as a base skeleton. SOLUTION: This glyoxalase I activity-inhibiting agent including compounds having a specific pharmacophore and the apoptosis-inducing agent based on the glyoxalase I-inhibiting activity are provided. COPYRIGHT: (C)2006,JPO&NCIPI