发明名称 |
Virus-like particles for the induction of autoantibodies |
摘要 |
The invention described herein relates to compositions and methods for stimulating immune responses in vivo against a tolerogen. Novel biotechnological tools, pharmaceuticals, therapeutics and prophylactics, which concern chimeric or conjugated virus-like particles, and methods of use the foregoing are provided for the study of B cell tolerance and the treatment or prevention of human diseases, which involve the onset of B cell tolerance, such as chronic viral infection, chronic inflammatory disease, and neoplasia. |
申请公布号 |
EP1637166(A3) |
申请公布日期 |
2006.04.12 |
申请号 |
EP20050027951 |
申请日期 |
1999.10.20 |
申请人 |
THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
发明人 |
SCHILLER, JOHN T.;CHACKERIAN, BRYCE;LOWY, DOUGLAS R. |
分类号 |
A61K47/48;C07K14/005;C07K16/24;C07K16/28;C07K17/00 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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