| 摘要 |
The present invention relates to gums, lozenges, candies, tablets, liquids and spray compositions that contain orally administered medications and dietary supplements that are released in the oral cavity. The medications and dietary supplements contained therein may be delivered in a multi-phase mode. The compositions may also contain buffer systems that facilitate oral absorption. A rapid release is followed by slower release of medicant(s) and dietary supplements. The buffer system is released simultaneously with the medicant(s) and dietary supplements, thereby facilitating transmucosal and buccal absorption of active ingredient(s). The invention delivers, first, rapidly an initial pharmacologically effective dose of medicine and dietary supplements and, second, a prolonged pharmacologically sufficient dose for longer-term relief of symptoms or provision of therapeutic effect.
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