摘要 |
Provided are compounds of a formula (I) and their pharmaceutically-acceptable salts:
wherein X1, X2 and X3 each independently represent N or CH; W represents the following formula (II):
or the following formula (III):
Y represents a group of a formula (IV):
The compounds have a histamine-H3 receptor antagonistic or inverse-agonistic activity and are useful for remedy and/or prevention of obesity, diabetes, hormone secretion disorders, sleep disorders, etc.
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申请人 |
BANYU PHARMACEUTICAL CO., LTD. |
发明人 |
OHTAKE, NORIKAZU;NAYA, AKIRA,;HAGA, YUJI,;JITSUOKA, MAKOTO;SUGA, TAKUYA,;YOSHIMOTO, RYO,;TOKITA, SHIGERU;KANATANI, AKIO, |