摘要 |
<p>4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds, pharmaceutical compositions containing such compounds and the use of such compounds to elevate certain plasma lipid levels, including high density lipoprotein-cholesterol and to lower certain other plasma lipid levels, such as LDL-cholesterol and triglycerides and accordingly to treat diseases which are exacerbated by low levels of HDL cholesterol and/or high levels of LDL-cholesterol and triglycerides, such as atherosclerosis and cardiovascular diseases in some mammals, including humans. Formula (I).</p> |
申请人 |
PFIZER PRODUCTS INC.;DIDIUK, MARY, THERESA;MAGNUS-ARYITEY, GEORGE, TETTEH;RUGGERI, ROGER, BENJAMIN;SHANKER, RAVI, MYSORE;THUMA, BENJAMIN, AARON;GARR, CHERYL, DENISE;LORENZ, DOUGLAS, ALAN |
发明人 |
DIDIUK, MARY, THERESA;MAGNUS-ARYITEY, GEORGE, TETTEH;RUGGERI, ROGER, BENJAMIN;SHANKER, RAVI, MYSORE;THUMA, BENJAMIN, AARON;GARR, CHERYL, DENISE;LORENZ, DOUGLAS, ALAN |