3-Acylaminocaprolactams containing a mono- or poly-cyclic cyclo-alkane or -alkene group in the acyl moiety for treatment of inflammatory disorders

摘要

The invention provides compounds, compositions and uses of compounds of general formula (I) or pharmaceutically acceptable salts thereof, which are 3-aminocaprolactam derivatives, for the preparation of a medicament intended to treat an inflammatory disorder: wherein X is -CO-Y-(R<1>)n or SO2-Y-(R<1>)n; Y is a cycloalkyl or polycyloalkyl group (such as an adamantyl, adamantanemethyl, bicyclooctyl, cyclohexyl, cyclopropyl group); or is a cycloalkenyl or polycycloalkenyl group; R<1> is H or a substituent as defined in the application; and n is 1 to m where m is the maximum number of substitutions permissible on cyclo-group Y.