发明名称 2-benzoxazolyl benzene derivatives and their use as UV screening agents
摘要 Novel benzoxazolyl benzene derivatives of formula (I): wherein R<SUP>1 </SUP>is hydrogen, C<SUB>1-20</SUB>-alkyl or C<SUB>2-20</SUB>-alkenyl; R<SUP>2 </SUP>and R<SUP>3 </SUP>are independently a group -C(R<SUP>4</SUP>,R<SUP>5</SUP>)C(R<SUP>6</SUP>)-C(R<SUP>7</SUP>,R<SUP>8</SUP>) (a) or a group -C(R<SUP>4'</SUP>,R<SUP>5'</SUP>)CH(R<SUP>6'</SUP>)CH(R<SUP>7'</SUP>,R<SUP>8'</SUP>) (b), wherein R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>7</SUP>, R<SUP>8</SUP>, R<SUP>4'</SUP>, R<SUP>5'</SUP>, R<SUP>6'</SUP>, R<SUP>7'</SUP> and R<SUP>8'</SUP> are independently, hydrogen, C<SUB>1-10</SUB>-alkyl or C<SUB>2-10</SUB>-alkenyl, or C<SUB>2-10</SUB>-alkyl or C<SUB>3-10</SUB>-alkenyl containing at least one oxygen atom interrupting the hydrocarbon chain; or wherein R<SUP>4</SUP>, R<SUP>5</SUP>, R<SUP>6</SUP>, R<SUP>4'</SUP>, R<SUP>5'</SUP> and R<SUP>6'</SUP> are hydrogen, C<SUB>1-10</SUB>-alkyl or C<SUB>2-10</SUB>-alkyl containing at least one oxygen atom interrupting the hydrocarbon chain, or alkyl substituted by silane or oligosiloxane moiety, and one of R<SUP>7 </SUP>and R<SUP>8 </SUP>or R<SUP>7'</SUP> and R<SUP>8'</SUP> is a silane or oligosiloxane moiety and the other one of R<SUP>7 </SUP>and R<SUP>8 </SUP>or R<SUP>7'</SUP> and R<SUP>8'</SUP> is hydrogen; and X is phenylene or naphthylene, or substituted phenylene or naphthylene for use as UV screening agents for protecting human skin or hair against radiation, and in UV screening compositions, particularly topical compositions for cosmentic or dermatological use.
申请公布号 US7019020(B2) 申请公布日期 2006.03.28
申请号 US20030467430 申请日期 2003.08.04
申请人 DSM IP ASSETS B.V. 发明人 HUBER ULRICH
分类号 A61K31/423;C07D263/62;A61K8/00;A61K8/49;A61Q17/04;C07C233/75;C07D263/54;C07D263/64;C07F7/08;C09K3/00 主分类号 A61K31/423
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