DYNAMISCHE TEILCHENGRÖSSENKONTROLLE FÜR AEROLISIERTE ARZENEIVERABREICHUNG

摘要

A disposable container for use in aerosolized delivery of drugs to the lungs, comprising: a wall which is collapsible upon the application of force; an opening in the container, which opening is covered at least in part by a flexible porous membrane having pores with a diameter in the range of about 0.25 to about 6.0 microns, the membrane being sufficiently flexible such that it will protrude outward in a convex configuration upon the application of force; and a formulation comprised of a pharmaceutically active drug and a carrier, which formulation is characterised by its ability to form an aerosol of particles which can be inhaled into a patient's lungs when the formulation is moved through the pores of the membrane.