发明名称 PYRIDINALKYL-AMINOALKYL-IH-INDOLE DERIVATIVES HAVING AN INHIBITORY ACTION ON 5-HT AND SEROTONIN REUPTAKE AS ANTIDEPRESSANTS AND ANXIOLYTICS
摘要 Novel indole derivatives of the formula (I), in which X, Y, R<SUP>1</SUP>, R<SUP>1'</SUP>, m and n have the meanings indicated in Patent Claim 1 , have a strong affinity to the 5-HT<SUB>1A </SUB>and in some cases to the 5-HT<SUB>1D </SUB>receptors. The compounds inhibit serotonin reuptake, exhibit serotonin-agonistic and -antagonistic properties and are suitable as antidepressants, anxiolytics and for the treatment of neurodegenerative diseas
申请公布号 US2006063811(A1) 申请公布日期 2006.03.23
申请号 US20050535916 申请日期 2005.05.23
申请人 MERCK PATENT GMBH 发明人 HOELZEMANN GUENTER;SCHIEMANN KAI;HEINRICH TIMO;BOETTCHER HENNING;LEIBROCK JOACHIM;VAN AMSTERDAM CHRISTOPH;BARTOSZYK GERD
分类号 A61K31/4439;C07D401/12;C07D403/02 主分类号 A61K31/4439
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