发明名称 |
Nontoxic, immunologically crossreactive toxin A protein from Pseudomonas aeruginosa |
摘要 |
A nontoxic, immunologically crossreactive toxin A protein produced by a PAO-PR1 mutant strain of Pseudomonas aeruginosa. The protein, in activated form, has substantially no adenosine diphosphate-ribosylating activity, and is nontoxic to cells known to be susceptible to the parent PAO-1 strain of Pseudomonas aeruginosa from which strain PAO-PR1 was derived. The nontoxic toxin A protein is immunologically indistinguishable from, and has a molecular weight similar to, native toxin A protein produced by the PAO-1 strain.
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申请公布号 |
US4470924(A) |
申请公布日期 |
1984.09.11 |
申请号 |
US19810335993 |
申请日期 |
1981.12.30 |
申请人 |
IGLEWSKI, BARBARA M.;CRYZ, JR., STANLEY J. |
发明人 |
IGLEWSKI, BARBARA M.;CRYZ, JR., STANLEY J. |
分类号 |
A61K39/00;A61K39/104;C07K14/21;(IPC1-7):C07G7/00;A61K39/10;C12P21/00;C12N1/20 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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