| 摘要 |
<p num="1"><br/><br/><br/>The present application describes antibodies that selectively bind human <br/>FcgammaRIIB, with little or no binding to other human FcgammaRs, e.g., human <br/>FcgammaRIIA. The invention also provides isolated bispecific antibodies <br/>comprising an antibody that selectively binds FcgammaRIIB, and a second <br/>antibody that specifically binds an activating receptor. Various uses, <br/>including therapeutic uses, for those antibodies are also described, including <br/>administration with anti-tumor antibodies and methods of inhibiting immune <br/>responses and suppressing histamine release.<br/></p> |
