发明名称 |
APORPHINE AND OXOAPORPHINE AND THE MEDICAL USE THEREOF |
摘要 |
<p>The invention provides certain aporphine and oxoaporphine for preparing medicine which can be used for ischemic disease prevention and treatment. The pharmacological mechanism of said compounds is to keep or increase endothelial nitric oxide synthase (eNOS), thus, the compounds can be used to produce medicines to prevent or treat mammal or human's ischemic disease, including ischemic apoplcxia, ischemic cerebral thrombosis, ischemic cerebral embolism, hypoxic-ischemic encephalopathy, ischemic heart disease or ischemic intestinal lesion.</p> |
申请公布号 |
EP1634596(A1) |
申请公布日期 |
2006.03.15 |
申请号 |
EP20030732200 |
申请日期 |
2003.06.19 |
申请人 |
LOTUS PHARMACEUTICAL CO., LTD. |
发明人 |
SU, MINGJAI;LEE, SHOEISHENG |
分类号 |
C07D491/06;A61K31/473;A61K31/48;A61P7/02;C07D221/18;C07D491/04;(IPC1-7):A61K31/473 |
主分类号 |
C07D491/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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