发明名称 |
SCREENING-METHODE FÜR INHIBITOREN VON ACRAB UND ACRAB-ÄHNLICHEN AUSFLUSS-PUMPEN |
摘要 |
The instant methods and compositions represent an advance in controlling drug resistance in microbes. AcrAB-like efflux pumps have been found to control resistance in drugs, even in highly resistant microbes. Accordingly, the use of the inhibitors for the treating of infections or enhancing the antimicrobial activity of drugs are provided, along with compositions comprising the inhibitors, optionally in combination with an antimicrobial agent. |
申请公布号 |
AT319478(T) |
申请公布日期 |
2006.03.15 |
申请号 |
AT20000950577T |
申请日期 |
2000.07.21 |
申请人 |
TRUSTEES OF TUFTS COLLEGE |
发明人 |
OETHINGER, MARGRET;LEVY, STUART, B. |
分类号 |
G01N33/50;A61K31/00;A61K31/085;A61K31/496;A61K45/06;A61P31/00;A61P31/04;A61P43/00;C12Q1/02;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|