TARGETED EXPRESSION OF APOPTOSIS-INDUCING GENES FOR DISEASE TREATMENT
摘要
The invention provides materials and methods related to the use of recombinant nucleic acid molecules containing an expression control element of an inhibitor of apoptosis protein (IAP) gene operatively linked to a coding region for an active cytotoxic/cytolytic agent. The recombinant molecules are used in methods to treat a variety of diseases and disorders, including a wide range of cancers.
申请公布号
WO2006026451(A2)
申请公布日期
2006.03.09
申请号
WO2005US30451
申请日期
2005.08.26
申请人
CHILDREN'S HOSPITAL INC.;CALDAS, HUGO;ALTURA, RACHEL, A.