发明名称 |
Chemically-modified progenipoietin conjugates |
摘要 |
The present invention provides a chemically modified Progenipoietins (ProGPs) prepared by binding a water soluble polymer to the protein. The chemically-modified protein according to the present invention may have a much longer lasting neutrophil-increasing activity than that of the un-modified ProGP, enabling reduced dose and scheduling opportunities.
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申请公布号 |
US2006052291(A1) |
申请公布日期 |
2006.03.09 |
申请号 |
US20030481935 |
申请日期 |
2003.12.22 |
申请人 |
SIEGAL NED R;FINN RORY F;HILLS ROBERT L |
发明人 |
SIEGAL NED R.;FINN RORY F.;HILLS ROBERT L. |
分类号 |
A61K38/18;A61K47/34;A61K38/00;A61K38/20;A61K47/48;A61P7/00;A61P7/06;A61P7/08;C07K14/475;C07K14/52;C07K14/705;C12N5/06;C12N5/08;C12P21/06 |
主分类号 |
A61K38/18 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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