Antibodies to CD23, derivatives thereof, and their therapeutic uses

摘要

The invention relates to antibodies which bind to the CD23 (FCepsilonRII) type II molecule particularly altered antibodies including antibodies which bind to the CD23 (FCepsilonRII) type II molecule characterized by an affinity constant equal to or greater than 1x10⁹ Ka Mol^-1, the preparation of such antibodies, pharmaceutical compositions which contain such antibodies and their use in therapy particularly in the treatment of autoimmune and inflammatory disorders.