发明名称 COMPOUND AND METHOD FOR TREATMENT OF CARDIOVASCULAR INFLAMMATORY AND IMMUNE DISORDERS
摘要 PROBLEM TO BE SOLVED: To provide a new compound useful as an active ingredient of a medicine for cure or prevention of inflammatory disorders. SOLUTION: The compound is represented by formula (I), wherein Ar indicates phenyl, trimethoxyphenyl, dimethoxyphenyl, fluorophenyl or difluorophenyl; W indicates -AN(OM)C(O)N(R<SP>3</SP>)R<SP>4</SP>; A indicates a lower alkyl, lower alkenyl or lower alkynyl; X and Y indicate O (oxygen); m is 1 when A is a lower alkyl or lower alkenyl and is O when A is a lower alkynyl; M indicates hydrogen or a pharmaceutically allowable cation; R1, R2, R3 and R4 are each independently hydrogen or a lower alkyl. COPYRIGHT: (C)2006,JPO&NCIPI
申请公布号 JP2006056906(A) 申请公布日期 2006.03.02
申请号 JP20050323229 申请日期 2005.11.08
申请人 MILLENNIUM PHARMACEUTICALS INC 发明人 CAI XIONG;GREWAL GURMIT;HUSSOIN SAJJAT;FURA ABERRA;SCANNEL RALPH;BIFTU TESFAYE;QIAN CHANGGENG
分类号 C07D307/20;C07D333/28;A61K31/34;A61K31/341;A61K31/38;A61K31/381;A61K31/44;A61K31/4427;A61K31/443;A61K31/4433;A61P17/00;A61P29/00;A61P37/08;A61P39/06;A61P43/00;C07D207/04;C07D307/14;C07D307/16;C07D333/32;C07D401/04;C07D405/04;C07D409/04;C07D471/04 主分类号 C07D307/20
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