| 发明名称 |
GUANIDINO-SUBSTITUTED QUINAZOLINONE COMPOUNDS AS MC4-R AGONISTS |
| 摘要 |
A variety of small molecule, guanidine- containing molecules capable of acting as MC4-R agonists are provided. The compounds are useful in treating MC4-R mediated diseases when administered to subjects. The compounds have the structure IA, IB, and IC where the values of the variables are defined herein.
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| 申请公布号 |
KR20060018217(A) |
申请公布日期 |
2006.02.28 |
| 申请号 |
KR20057021301 |
申请日期 |
2005.11.09 |
| 申请人 |
CHIRON CORPORATION;GLAXOSMITHKLINE |
发明人 |
BOYCE RUSTUM S.;AURRECOECHEA NATALIA;CHU DANIEL;SMITH AARON;CONLEE CHRISTOPHER R.;THOMPSON BRIAN D.;DE ARMAS KUNTZ JUDITH;MUSSO DAVID L.;BARVIAN KEVIN K.;THOMSON STEPHEN A.;SWAIN WILLIAM R.;DU KIEN S.;CHAUDER BRIAN A.;SPEAKE JASON D.;BISHOP MICHAEL J. |
| 分类号 |
C07D403/12;A61K31/517;A61K31/519;A61K31/525;A61K31/53;A61P3/04;A61P3/10;C07D217/24;C07D239/91;C07D239/95;C07D239/96;C07D253/08;C07D401/04;C07D401/06;C07D401/12;C07D401/14;C07D403/04;C07D403/06;C07D403/14;C07D405/12;C07D417/04;C07D417/14;C07D471/04;C07D475/02;C07D487/02;C07D487/04 |
主分类号 |
C07D403/12 |
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